產品介紹

bioGenous?  人氣管類器官（分化型）培養試劑盒是一種專為分化人氣道干細胞來源的人氣道類器官（hAOs）而設計的無血清培養基。在分化條件下培養 10–14 天后，氣道類器官可形成清晰的管腔結構，顯微鏡下可觀察到明顯的纖毛搏動或分泌物積聚現象。分化的 hAOs 展現出成熟氣道上皮的關鍵結構與功能特征，包括：運動纖毛中高水平表達微管蛋白（tubulin），以及黏液分泌型杯狀細胞中高表達 MUC5AC。結合 bioGenous?  人氣管類器官（擴增型）培養試劑盒使用，該分化體系可在體外高效、穩定地重建氣道上皮，廣泛支持呼吸系統研究、毒理學評估、藥物研發及再生醫學等多領域應用。

Product Description

bioGenous? Human Airway (Differentiation) Organoid Kit is a serum-free culture medium designed for the differentiation of human airway organoids (hAOs) derived from human airway stem cells. When cultured in differentiation conditions for 10-14 days, airway organoids develop well-defined luminal structures, within which extensive ciliary beating or accumulation of secretory material can be observed under the microscope. Differentiated hAOs exhibit key functional and structural features of the mature airway epithelium, including high expression of tubulin in motile cilia and MUC5AC in mucus-secreting goblet cells. In combination with bioGenous? Human Airway (Expansion) Organoid Kit, this differentiation system enables robust and reproducible generation of airway epithelium in vitro, supporting a wide range of applications in respiratory research, toxicology, drug discovery, and regenerative medicine.