類器官基質膠

Organoid Culture ECM (Reduced Growth  Factor) 

產品介紹

bioGenous? 類器官培養基質膠是一種從 Engelbreth-Holm-Swarm（EHS）小鼠肉瘤中提取并純化的可溶性基底膜基質，主要成分包括層粘連蛋白（laminin）、IV 型膠原（collagen IV）、巢蛋白（nidogen/entactin）和硫酸乙酰肝素蛋白聚糖（heparan sulfate proteoglycan）。

本品為低生長因子型（Reduced Growth Factor, RGF）基質膠，可最大程度減少外源因子干擾，便于精確調控類器官培養微環境，提升實驗重復性和數據一致性。適用于人胚胎干細胞（hESCs）、成體干細胞及各類組織來源的健康或腫瘤類器官的 3D 培養與長期維持。

該基質膠與所有常用培養基兼容，在 10°C 以上即可成膠，操作簡便，是類器官、類胚體（embryoid bodies）及體內移植實驗的理想支撐基質。

Product Description

Basement membranes are thin continuous layers of specialized extracellular matrices that form the interface on which epithelial, endothelial, or neuronal cells grow. Basement membranes also support muscle and Schwann cells of the peripheral nerves as they are found surrounding these cells. The bioGenous^TM Organoid Culture ECM is a soluble form of basement membrane extracted and purified from the Engelbreth-Holm-Swarm (EHS) tumor. The major constituents of the bioGenous^TM Organoid Culture ECM include laminin, collagen IV, entactin/nidogen, and heparin sulfate proteoglycan.

bioGenous^TM Organoid Culture ECM is a reduced growth factor hydrogel that allows the complete control of the organoid culture microenvironment to allow for more consistent cell growth and reproducible experiments. It supports the growth and maintenance of human embryonic stem cells (hESCs) and tissue-derived stem cells, and for the in vivo study of both healthy and tumor organoids derived from various organs. bioGenous^TM Organoid Culture ECM is compatible with all culture media and gels at temperatures above 10°C to form a reconstituted basement membrane.

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