Product Description

bioGenous? Human Intestinal Organoid Kit is a serum-free culture medium specifically designed for long-term culture of human intestinal organoids derived from adult stem cells. The medium supports self-renewal of intestinal epithelium by promoting the proliferation of stem cells and their progenitors located within the crypts. Organoids cultured in human intestinal organoid expansion medium predominantly exhibit LGR5+ stem cells, cycling transit-amplifying cells (TA), early enterocytes, while the human intestinal organoid maintenance medium could support a small number of goblet cells. These organoids replicate the architecture and cell type composition of the intestinal epithelium, making them invaluable for groundbreaking research into human intestinal development and disease modeling. The versatility of human intestinal organoid enables their application in various research domains, including cell biology, cancer research, intestinal immunology, and regenerative biology through ex vivo expansion of the intestinal epithelium.