bioGenous? 小鼠小腸類器官培養試劑盒是一種專為成年小鼠腸干細胞來源的腸道類器官設計的無血清培養基。在該完全培養基中培養的類器官主要由以下細胞組成：腸道干細胞（LGR5+）、快速增殖細胞（KI67+）、吸收性腸上皮細胞（ALPI+）、潘氏細胞（ATOH1+）和杯狀細胞（MUC2+）。這些小鼠腸道類器官能夠高度重現體內腸道上皮的自我更新能力、組織結構、細胞類型組成及功能特性，因此是研究腸道穩態與疾病機制的理想體外模型。

Product Description

bioGenous? Mouse Intestinal Organoid Kit is a serum-free culture medium designed for mouse intestinal organoids derived from adult intestinal stem cells. Organoids grown in this complete medium predominantly consist of intestine stem cells (LGR5+), rapidly proliferating cells (KI67+), absorptive enterocytes (ALPI+), Paneth cells (ATOH1+), and goblet cells (MUC2+). These mouse intestinal organoids faithfully recapitulate the characteristics of in vivo intestinal epithelium in terms of self-renewal capacity, tissue architecture, cell type composition, and functionality. Therefore, they serve as an ideal in vitro model for studying intestinal homeostasis and disease mechanisms.