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<C665752> 伯楨生物(bioGenous) Forskolin

欄目：生長因子及小分子（用于類器官培養）
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Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase[1]. Forskolin is also an inducer of intracellular cAMP formation[2]. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR[3]. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy.

Forskolin


        產品編號        

         產品名稱       

        包裝規格        

     價格     

C665752   

Forskolin

50mg

2424

產品介紹

Background

Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy.

Alias

毛喉素; Coleonol; Colforsin

M. W t

410.50

Formula

C22H34O7

CAS No

66575-29-9

Storage

Powder

-20°C  

3 years                          

In solvent

-80°C 

6 months                                 

-20°C      

1 month

Solubility

DMSO

100 mg/mL(243.61 mM; Need ultrasonic)

Ethanol

82 mg/mL(199.76 mM)

H2O

< 0.1 mg/mL(insoluble)