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<816-FGF> 伯楨生物(bioGenous) Recombinant Human FGF10

欄目:生長因子及小分子(用于類器官培養)
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FGF-10 belongs to the subgroup of FGFs that also includes FGF-3, -7, and -22. FGF-10 is secreted by mesenchymal cells and associates with extracellular FGF-BP. It preferentially binds and activates epithelial cell FGF R2 (IIb) and interacts more weakly with FGF R1 (IIb).

Recombinant Human FGF10


產品編號

產品名稱

     包裝規格     

    價格    

      816-FGF-1mg         

      Recombinant Human FGF10      

1mg

10494

816-FGF-100ug

Recombinant Human FGF10

100μg

1799


產品介紹

FGF-10 belongs to the subgroup of FGFs that also includes FGF-3, -7, and -22. FGF-10 is secreted by mesenchymal cells and associates with extracellular FGF-BP. It preferentially binds and activates epithelial cell FGF R2 (IIb) and interacts more weakly with FGF R1 (IIb). The expression and function of FGF-10 are negatively regulated by Shh and BMP-4 in the developing lung. Overlapping expression patterns and activities with FGF-3, -7, and -8 suggest at least a partial redundancy in FGF-10 biology. FGF-10 induced signaling through FGF R2 (IIb) also contributes to the progression of pancreatic cancer.