Recombinant Human FGF10
產品編號 | 產品名稱 | 包裝規格 | 價格 |
816-FGF-1mg | Recombinant Human FGF10 | 1mg | 10494 |
816-FGF-100ug | Recombinant Human FGF10 | 100μg | 1799 |
產品介紹
FGF-10 belongs to the subgroup of FGFs that also includes FGF-3, -7, and -22. FGF-10 is secreted by mesenchymal cells and associates with extracellular FGF-BP. It preferentially binds and activates epithelial cell FGF R2 (IIb) and interacts more weakly with FGF R1 (IIb). The expression and function of FGF-10 are negatively regulated by Shh and BMP-4 in the developing lung. Overlapping expression patterns and activities with FGF-3, -7, and -8 suggest at least a partial redundancy in FGF-10 biology. FGF-10 induced signaling through FGF R2 (IIb) also contributes to the progression of pancreatic cancer.